en فیزیولوژی ورزشی Sport Physiology تحقيقي Original Paper <div style="text-align: justify;"><span style="font-family:Times New Roman;"><span style="font-size:12px;"><span style="line-height:200%"><span calibri=""><b><span style="line-height:200%"><span new="" roman="" times="">Background:</span></span></b><span style="line-height:200%"><span new="" roman="" times=""> Coronary artery bypass graft (CABG) is a surgical procedure used to treat coronary heart disease. The present study aimed to investigate effects of 8 weeks of combined rehabilitation training on plasma levels of leptin, adiponectin, and resistin in middle-aged men who have undergone CABG.</span></span></span></span><br> <span style="line-height:200%"><span calibri=""><b><span style="line-height:200%"><span new="" roman="" times="">Methods:</span></span></b><span style="line-height:200%"><span new="" roman="" times=""> The present research was a quasi-experimental study with a pretest-posttest design. The statistical population included all patients who have undergone CABG in Mashhad, Iran. Overall, 26 middle-aged men who have undergone CABG were enrolled in the study. The subjects were divided into a training group (n=14) and a control group (n=12). Data were analyzed in SPSS software (version 21) using analysis of covariance and paired t-test at significance level of 0.05.</span></span></span></span><br> <span style="line-height:200%"><span calibri=""><b><span style="line-height:200%"><span new="" roman="" times="">Results</span></span></b><span style="line-height:200%"><span new="" roman="" times="">: Plasma levels of leptin did not change significantly (<i>p</i>=0.709), adiponectin increased significantly (<i>p</i>=0.001), and resistin decreased significantly (<i>p</i>=0.005) after the training intervention.</span></span></span></span><br> <span style="line-height:200%"><span calibri=""><b><span style="line-height:200%"><span new="" roman="" times="">Conclusion</span></span></b><span style="line-height:200%"><span new="" roman="" times="">: As a non-pharmacological intervention, the rehabilitation training has cardioprotective effects on patients who undergone CABG.</span></span></span></span></span></span></div> Rehabilitation,Leptin,Adiponectin,Resistin, 20 26 http://mlj.goums.ac.ir/browse.php?a_code=A-10-1057-1&slc_lang=en&sid=1 Hossein Nikkar h.nikkar@iau-neyshabur.ac.ir 100319475328460031938 100319475328460031938 No Department of Exercise Physiology, Neyshabur Branch, Islamic Azad University, Neyshabur, Iran. Amir Rshidlamir amir.rashidlamir@gmail.com 100319475328460031939 100319475328460031939 No Department of Exercise Physiology, Faculty of Sport Sciences, Ferdowsi University of Mashhad , Mashhad, Iran. Rambod Khajei r.khajeie@gmail.com 100319475328460031940 100319475328460031940 Yes Department of Exercise Physiology, Neyshabur Branch, Islamic Azad University, Neyshabur, Iran Amene Barjaste barjaste.a7@gmail.com 100319475328460031941 100319475328460031941 No Department of Exercise Physiology, Neyshabur Branch, Islamic Azad University, Neyshabur, Iran. Mohsen Vazifedoost m.vazifedoost@iau-neyshabur.ac.ir 100319475328460031942 100319475328460031942 No Department of Food Science and Technology, Neyshabur branch, Islamic Azad University, Neyshabur, Iran